Compassionate care for every stage of your Polyendocrine Metabolic Ovarian Syndrome (PMOS, formerly known as PCOS) journey.
Polyendocrine Metabolic Ovarian Syndrome (PMOS), formerly known as Polycystic Ovarian Syndrome (PCOS), is a complex hormonal condition that is thought to affect between 5 and 15% of people of reproductive age. However, the number may be even higher, as up to 70% of women with the condition worldwide remain undiagnosed.
It occurs in women who have a combination of insulin resistance and elevated androgen (male-type hormone) levels. They develop small, hormonally active follicles on each ovary that are cyst-like in appearance. This may prevent follicles (which contain an egg cell) from growing and maturing as they should.
PMOS has been associated with multiple medical issues (including abnormal periods and excess hair growth), which may make it challenging to manage. Create Fertility specialises in PMOS and has helped many women with this condition to achieve their health and reproductive goals.
The symptoms of PMOS are many and varied; however, some of the more common symptoms include:
Women with PMOS may be more prone to developing diabetes and cardiovascular disease.
While not everyone with PMOS will experience fertility issues, it has been known to cause issues for some women.
A woman who is not regularly ovulating or not ovulating at all may find it harder to fall pregnant naturally.
High androgen levels may stop follicles from developing properly, leading to a build-up of immature eggs in the ovaries. It’s okay to have some, but too many may make it hard to conceive.
High insulin levels may affect the menstrual cycle and ovulation.
Being overweight may further disrupt hormone levels, which may negatively impact fertility.
Some studies have indicated that PMOS may lead to a higher rate of miscarriage
There are several ways that you may be able to manage your PMOS symptoms and their impact. Our team will create a comprehensive treatment plan based on your specific symptoms and their severity.
Our treatment options include:
For women also wanting to fall pregnant, there are several potential treatment options, including:
While there are surgical options for inducing ovulation available, they are usually reserved for patients who have not had success with less invasive approaches and who have a lot of follicles in their ovaries.
While the exact cause of PMOS is unknown, several factors may contribute to its development. These include genetics (as it tends to run in families) and insulin resistance. Inflammation and lifestyle factors (such as poor diet, lack of exercise, and high stress levels) may contribute to insulin resistance and/or exacerbate symptoms.
Diagnosis typically occurs when at least two of the following symptoms are present:
PMOS may be associated with some long-term health risks, including insulin resistance, increased risk of developing diabetes, cholesterol and high blood pressure, or cardiovascular disease. The absence of periods long term, can lead to cancer of the lining of the uterus (endometrial cancer). Early diagnosis of PMOS is important, as it may allow for symptom management and prevent long-term disease from developing.
Yes, it may increase the risk of complications during pregnancy. These may include early miscarriage, gestational diabetes, pre-eclampsia, premature delivery, and caesarean delivery. Women with PMOS may require extra care before, during, and after pregnancy, so it is important to discuss your circumstances with your fertility clinic.
PMOS can be complex, but getting the right care shouldn’t be. At Create Fertility, our team provides evidence-based guidance designed to help you manage symptoms and understand your fertility potential.
We are committed to supporting you through every stage, from diagnosis to treatment and family planning decisions. With experienced specialists and a warm, patient-first approach, we aim to help you move forward with clarity.
Contact us to book a consultation and start your journey today.
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Date: Wednesday 19 November 2025
Time: 7:00 PM AEDT
Location: Live via Microsoft Teams
Cost: Free